关键词: PSA, 肿瘤标志物, 前列腺癌, 诊断

Abstract: 【Abstract】〓Objective〓To investigate the clinical value of different PSA-related tumor markers in prostate cancer. Methods〓A retrospective clinical data were analyzed in 300 cases of suspected prostate cancer patients in Zhongshan Traditonal Chinese Medical Hospital from January 2011 to December 2014. According to the results of transrectal prostate biopsy, the patients were divided into two groups, prostate cancer group (n=84) and non-prostate cancer (212). The levels of F-PSA/T-PSA, PSAD and (F-PSA T-PSA)/PSAD were compared between two groups and assessed the diagnostic value of these indicators. Results〓The results of F-PSA/T-PSA, PSAD and (F-PSA/T-PSA)/PSAD showed statistically significant differences between two groups (P<0.05). (F-PSA/T-PSA)/PSAD showed the highest specificity for the diagnosis of prostate cancer in all of parameters (P<0.05). Conclusion〓in the present study, the high level of (F-PSA/T-PSA)/PSAD has diagnostic significance for early prostate cancer and showed high specificity.

Key words: PSA, Tumor markers, Prostate cancer, Diagnosis