关键词: 肝细胞癌, 胆管细胞癌, 动物模型, 进展

Abstract: 【Abstract】〓Animal model is a fundamental and useful tool in tumor research. As a substitute, it provides a good condition for the researching of etiology, pathology, physiology and micro environment in tumor progress. The efficacy of new treatments can also be verified by tumor model preclinically. Hepatocellular carcinoma and cholangiocarcinoma confirmed as two subtypes of primary liver cancer, the methods for constructing animal models have both similarities and differences which will be summary analyzed in this article.

Key words: Hepatocellular carcinoma, Cholangiocarcinoma, Animal model, Advance