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岭南现代临床外科 ›› 2015, Vol. 15 ›› Issue (02): 135-138.DOI: 10.3969/j.issn.1009-976X.2015.02.003

• 论著与临床研究 • 上一篇    下一篇

吉非替尼治疗转移性乳腺癌个案报道及文献复习

林潇 丁林潇潇 丁林 姚和瑞   

  1. 中山大学孙逸仙纪念医院
  • 通讯作者: 姚和瑞

Gefitinib treatment in metastic breast cancer:.case report and review of the literature

Lin Xiao, Ding Linxiaoxiao, Ding Lin, Yao Herui   

  • Received:2015-01-29 Revised:2015-03-17 Online:2015-04-20 Published:2015-06-20

摘要: 【摘要】〓我国乳腺癌的发病率在女性恶性肿瘤里发病率居于第1位。分子靶向治疗药物成为近年来肿瘤治疗中的一大热点,表皮生长因子受体酪氨酸激酶抑制剂吉非替尼是EGFR敏感突变型非小细胞肺癌的标准一线治疗。近几年国外有临床研究显示吉非替尼对乳腺癌有一定治疗效果,但目前国内此类相关临床研究较少。现将我科诊治的一例吉非替尼治疗转移性乳腺癌的病例报告如下并做文献复习。

关键词: 乳腺癌, 转移, 靶向治疗

Abstract: 【Abstract】〓Breast cancer is the most common cancer in women,which continues to be a major cause of morbidity among women in China..Molecular-targeted therapyhas become a critical focus of cancertherapy..Gefitinib is a specific inhibitor of epidermal growth factor receptor-associated tyrosinekinase, which has been commonly used in the standard first-line treatment for NSCLC patients with EGFR mutations..Recently,several foreign clinical studies show that gefitinib is active in patients with breast cancer, but present domestic related clinical researches are extremely rare. We describe the case of a patient that was diagnosed with metastatic breast cancer treated with gefitinib therapy.

Key words: Breast Cancer, Metastatic, Target therapy

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