关键词: 全髋关节置换术, 假体, 金属-聚乙烯, 磨损, 骨溶解

Abstract: 【Abstract】〓Objective〓To investigate the clinical outcome of patients underwent total hip arthroplasty (THA) on the polyethylene wear of metal on polyethylene (MOP). Methods〓Between May 2003 and November 2008,.84 patients in Changshu NO.1 Hospital with MOP THA were reviewed. All patients were divided into A group (age <50 years and active patient) and B group (age≥50 and nonactive patient ) according to the age and activity. The A group received 35 patients (39 hips). The B group received 49 patients(49 hips). All prosthesis were composed by drill chromium molybdenum alloy and high-molecular-weight polyethylene..The clinicalresults were assessed by the Harris Hip Score..The radiographic results include the occurrence of bearing wear and osteolysis. The survival of the prosthesis was ended with radio graphically loosening or revision. Results〓All patients were followed up at least 5 years. In the group A, 3 cases and 3 hips (7.7%) have undergone revision but there were no revision in the group B. All the two groups have no complications like fracture, infections,.or DVT..The average Harris Hip Score of the preoperativepatients in the group A was 34.13±6.28, which improved to 91.35±2.68 postoperatively, and the Harris Hip Score in the B group was from 35.51±5.32 preoperatively to 90.05±2.47 postoperatively. The mean wear of the MOP bearing in the group A was 0.19±0.24 mm/y and which was 0.09±0.13 mm/y in the B group. There were remarkable differences in the two groups(P<0.05). Osteolysis accured in all cases in the A group, and 63.16% cases in the group B. The Osteolysis in B group significantly less than which in the A group (P<0.05). Conclusion〓There were more occurrence of bearing wear, osteolysis and the radiographical loosening in the young active patients than which in the old nonactive patients. So MOP prosthesis should be chosen carefully in the young patients.

Key words: Total hip arthroplasty, Prosthesis, MOP, Wear, Osteolysis