关键词: 复发, 肉芽肿性乳腺炎, 激素, 免疫抑制, 分支杆菌

Abstract: 【Abstract】〓Objective〓To introduce the diagnosis and treatment of refractory idiopathic granulomatous mastitis (IGM) and related literature review. Methods〓Three patients were complained of breast lump with redness and local ulceration even fistula formation. The pus bacteria culture were all negative...Two patients were given systemic therapy with corticosteroids and ‘Triple-anti mycobacterial therapy'. One case was treated with methyl prednisolone combined with methotrexate. Results〓There was no recurrence in follow-up for ten months. One case finally underwent wide excision and nipple retraction diorthosis and cured. The other two were both cured by conservative treatment. Conclusion〓‘Triple-anti mycobacterial therapy' or immunosuppressive agent combined with steroid therapy were effective approach for refractory IGM, but it was difficult and debatable to obtain the former medical evidence.

Key words: Granulomatous mastitis, Corticosteroid, Immunosuppressive, Mycobacteria, Reflapse