关键词: 艾滋病, 铜绿假单胞菌, 机会性感染, 耐药性

Abstract: 【Abstract】〓Objective〓To investigate differences in infective pathway, clinical manifestations and drug susceptibility results of pseudomonas aeruginosa infections between AIDS and non-AIDS patients, for improving diagnosis and treatment. Methods〓Totally 32 AIDS patients with pseudomonas aeruginosa infections from Jan..2010 to Aug..2014 were selected as the research subjects in observation group,and another 27 non-AIDS patients with pseudomonas aeruginosa infections during the same period were selected as the control group..Differences of two groups in infective pathway,.clinical manifestations and drug susceptibility results were compared and analyzed..Results〓The primary infective pathway of two groups was the same and derived from respiratory tract infection..The main clinical manifestations of observation group were fever,.cough and sputum..The clinical manifestations of control group were more complicated.. Twenty strains (62.5%) of pathogens were isolated from the patients of observation group,.and 24 strains(88.9%) were isolated (P<0.05) from control group..In the observation group, P.aeruginosa had a low resistance to imipenem and meropenem..In the control group,.P.aeruginosa had a relatively low resistance to amikacin,.cefotaxime and meropenem..Conclusion〓The difference of clinical manifestation and drug susceptibility results were significant between pseudomonas aeruginosa infections between AIDS and non-AIDS patients..Clinician should analyse the different conditions of patients comprehensively and choose the antibiotics reasonably.

Key words: AIDS, Pseudomonas aeruginosa, Opportunistic infections, Antibiotic resistance