关键词: 炎性肌纤维母细胞, 腹腔肿瘤

Abstract: 【Abstract】〓Objective〓To investigate the clinical features, pathological features, treatment options and prognosis of intra-abdominal inflammatory myofibroblastic tumor (IMT). Methods〓Five cases of intra-abdominal inflammatory myofibroblastic tumor from our hospital during June 2008 to May 2013 were analyzed and followed-up with the clinical features,pathological morphology, immunohisto-chemistry and treatment programs. Results〓The patients were included in 2 males and, 3 females, aged from 31 to 74 years old, and the mean age was 53.4 years old. The main symptoms are abdominal mass. All cases underwent surgical resection and the diagnosis was confirmed by pathological examination. The follow-up ranged from 6 months to 5 years, including one case of local recurrence. 3 cases of tumors derived from omentum, and 2 from mesentery. Immunohistochemistry showed that Actin, Vimentin and SMA were positive, while S-100, CD117 and, CD34 were negative. Conclusion〓The pathogenesis of IMT is not clear. The symptoms tend to disappear after surgical resection. Surgical resection is the primary approach in treatment of IMT. Considering the biological feature of the intermediate type of neoplasm in IMT, it needs to be followed-up closely.

Key words: Inflammatory myofibroblastic tumor, Intra-abdominal tumor