关键词: 舒芬太尼, 伤口浸润, 小儿术后镇痛

Abstract: 【Abstract】〓Objective〓To evaluate the analgesia effect of intravenous sufentanil in combination with ropivacaine infiltration and intravenous sufentanil for postoperative analgesia in pediatric laparotomy. Methods〓Eighty children aged 1-4 year scheduled for elective laparotomy were allocated randomly to 2 group. Group S+R received 0.25% ropivacaine wound infiltration according to the length of the wound(1 ml·cm^{-1) before skin closure and intravenous sufentanil 0.03 μg·kg-1·h-1 after operation, and group S received only intravenous sufentanil 0.03 μg·kg-1·h-1 for postoperative analgesia. The pain density was determined by FLACC at 1, 2, 4, 8, 12, 24, 48 h postoperatively. Results〓The pain score were significantly higher in group S when compared with group S+R at 1, 2, 4, 8 h postoperatively (P<0.05). There were no difference in the pain score at 12, 24, 48 h. Severe adverse events were not observed in the present study. Conclusion〓Intravenous sufentanil in combination with ropivacaine wound infiltration provided excellent and safe postoperative analgesia in pediatric laparotomy.}

Key words: Sufentanil, Wound infiltration, Pediatric postoperative analgesia