关键词: 非肝细胞癌肝脏局灶性病变, 超声造影, 诊断价值

Abstract:

【Abstract】〓Objective〓To explore the value of contrast-enhanced ultrasound (CEUS) in diagnosis of non-hepatocellular carcinoma(HCC).focal liver lesion.(FLL)..Methods〓CEUS characterizations of 1753 cases with non-HCC FLL were retrospectively analyzed. All cases were compared to the gold standard and collected from four hospitals..The diagnostic value of CEUS differentiating non-HCC FLL was evaluated between benign and malignant tumor, and different type of lesion were evaluated. Results〓In 1753 non-HCC FLL,.1318 cases were benign lesions,.of which 92.94% (1225/1318) benign lesions were diagnosed correctly by CEUS; 435 cases were malignant lesions,of which 88.74%(386/435).malignant lesions were diagnosed correctly by CEUS..The sensitivity, specificity, accuracy rate, positive predictive value and negative predictive value of CEUS were 88.74% (386/435),.92.94% (1225/1318), 91.90% (1611/1753), 80.58% (386/479), 96.15% (1225/1274), respectively..The CEUS diagnosis was correct in 97.41% of hemangiomas (640/657), in 96.43% focal fatty sparings and deposits (216/224), in 84.81% of metastatic liver cancer (268/316), 85.55% of focal nodular hyperplasia (225/263), 58.82% of inflammatory lesions (40/68),.57.14% of regenerative nodule (28/49) and 12.50% of dysplastic nodule (2/16). Conclusion〓CEUS is more reliable in differentiating between benign and malignant non-HCC FLL, but qualitative diagnosis accuracy of lesions type needs to be improved.

Key words: Non-hepatocellular carcinoma focal liver lesions, Contrast-enhanced ultrasound, Diagnostic value