关键词: 球蛋白(G)/胆碱脂酶(C)比值, Child-Pugh分级, 肝储备功能, 肝功能不全

Abstract: 【Abstract】〓Objective〓To investigate a method for predicting sensitively and specifically hepatic insufficiency by comparing globulin/cholinesterase(G/C) ratio with Child-Pugh scores in advance of hepatec-tomy in liver cancer patients. Methods〓We recruited patients retrospectively from May 2012 to January 2014 undergoing HCC hepatectomy in Sun Yat-Sen University Memorial Hospital,.including 138 males and 36 females. The study was conducted by analysis of G/C ratio compared with A,.B and C levels of Child-Pugh classification respectively. Results〓G/C ratio had positive relationship with Child-Pugh classification in evaluating preo-perative liver function(r=0.307, P<0.05). G/C ratio (OR=4.668, P=0.04) preceded Child-Pugh classification (OR=2.909, P=0.126) in predicting incidence of postoperative hepatic insufficiency. Conclusion〓In our present study, G/C ratio had positive correlation with Child-Pugh classification in evaluating liver reserve function preoperatively in HCC patients, but the former was superior to Child-Pugh classification in predicting hepatic insufficiency postoperatively.

Key words: Globulin(G)/cholinesterase(C) ratio, Child-Pugh classification, Liver reserve function, Hepatic insufficiency