关键词: 经导管主动脉瓣置换术, 人工瓣膜-患者不匹配, Meta分析

Abstract: 【Abstract】〓Objective〓Prosthesis-patient mismatch (PPM) leads to increased left ventricle afterload and influences the clinical outcome of postoperative patients. This Meta analysis aims to study risk factors of prosthesis-patient mismatch (PPM) after transcatheter aortic valve implantation (TAVI). Methods〓The data of prosthesis-patient mismatch after transcatheter aortic valve implantation was derived by searching Medline, Cochrane library, Scopus database. Studies with baseline data of PPM group and no PPM group were included in the Meta analysis. Results〓PPM patients had averaged body surface area of 1.87±0.202 m2,.age of 78.3±7.78 years old,.left ventricle ejection fraction of 41.0±14.1%,.effective orifice area index of 0.366±0.0922..Comparing with no PPM group,.PPM patients had larger body surface area,.lower left ventricle ejection fraction and lower effective orifice area (P<0.05)..No significant statistical differences of the other factors were found,.including sex,.body metabolic index,.preoperative acute myocardial infarction,history of coronary artery bypass graft,.NYHA grade,logistic EuroSCORE,transvalvular gradient,aortic annulus diameter(P>0.05). Conclusion〓Larger body surface area,lower left ventricle ejection fraction and more severe aortic stenosis are related to PPM.

Key words: Transcatheteraortic valve implantation (TAVI), Prosthesis-patient mismatch (PPM), Meta analysis