关键词: 胰岛素瘤, 围手术期管理, 全身麻醉, 血糖, 持续静脉泵注

Abstract:

【Abstract】 Objective To investigate the perioperative management for surgical removal of pancreatic insulinoma. Methods From November 2011 to October 2012,.the clinical data of 18 patients with insulinoma treated by surgical operation were analyzed retrospectively. Results Six male and 12 female patients with Whipple‘s triad were included into this study..Of 18 cases, fifteen patients received open tumor enucleation, and 3 cases received laparoscopic resection of the tumor. Patients underwent open surgery were anesthetized by general anesthesia combining with epidural block..Those underwent laparoscopic surgery received general anesthesia only. The patients were divided into 2 groups:.C group (n=10), patients received 50% GS continuous infusion and blood sugar was measured in every 15 min. 50% GS infusion ended 30 min before the removal of the tumor. NC group (n=8), patients didn’t receive 50% GS continuous infusion but just received 50% GS 50 mL intravenous injection when blood sugar was lower than 2.8 mmol·L-1. Vital signs were steady and blood sugar of patients in C group was controlled more stable than that NC group(P<0.05). Conclusion 50% GS infusion with repeat blood sugar monitoring intraoperatively would prevent dramatic hypoglycemia before and after tumor removal.

Key words: Insulinoma, Perioperative management, General anesthesia, Blood sugar, Continuous intravenous infusion